Aunt / Uncle Test Case Studies

Situations where AccuPlex DNA succeeded where a lesser test failed.

 

The best case scenario is to test the aunt or uncle, mother and child to ensure conclusive results about the father. We recognize that it’s not always possible to test all three, however, it is possible to take a statistical approach by testing the aunt or uncle and child.

When less people are tested, more markers are needed. The following case studies illustrate the power of testing more markers.

Case Example #1

 

An alleged aunt and child were tested using the 16 marker test. The results were a probability of relationship at 43.47%, which is too low to be conclusive. In this case, the participants did the right thing by adding the mother into the analysis but still ended up with inconclusive results. After testing 41 markers, the probability of relationship increased to 91.43%.

Case Example #2

 

An alleged uncle and a male child were compared with the 16 marker test and the probability of relationship was found to only be 23.90%. We performed a Y-chromosome test, which is a male specific DNA test, and found that they shared an identical Y-chromosome profile (a 99.97% probability of being part of the same paternal line). We also tested the two individuals with the 41 marker test and found that the probability of relationship increased from 23.90% with the 16 marker test to 89.81% with the 41 marker test.

Case Example #3

 

In this case, the alleged aunt and child were tested with the 16 marker test and the probability of relationship was only 27.26%. The mother was added and the probability change to 14.25%. It appeared that the alleged aunt was more likely to be unrelated. We applied the 41 marker test on the three participants and found that the probability of relationship was 96.24%. The dramatic change likely due to the fact that 16 markers was not enough. Incidentally, we also analyzed just the alleged aunt and child at 41 markers without the mother and found the probability of relationship to be 90.24%.